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tace联合动态ct引导微波消融治疗小肝细胞癌 -ag捕鱼平台

文字: 2020-6-4    浏览次数:321    


abstract

to evaluate the method and effectiveness of transcatheter arterial chemoembolization (tace) combined with simultaneous dynact-guided microwave ablation (mwa) for the treatment of small hepatocellular carcinoma (shcc).

评价经导管动脉化疗栓塞(tace)联合动态ct引导微波消融(mwa)治疗小肝癌(shcc)的方法和疗效。


from june 2015 to may 2017, a total of 28 consecutive patients with shcc received single treatment of tace and 23 subjects received a combination treatment of tace with simultaneous dynactguided mwa. following 1 month of treatment, the tumor response was assessed using the mrecist criteria and the outcomes were analyzed including intervention-associated complications, changes in liver function, imaging response, and progression-free survival (pfs).

自2015年6月至2017年5月,28例shcc患者接受单次tace治疗,23例患者同时接受动态ct引导 mwa联合tace治疗。治疗1个月后,使用mrecist标准评估肿瘤进展情况,同时分析相关预后指标,包括介入相关并发症、肝功能改变、影像学改变和无进展生存期(pfs)。


the technical success rate was 100%. the rates of cr (65%) in the combined tace and mwa group were higher than those of the tace group (46%). the rate of common adverse events, such as liver abscess, spontaneous bacterial peritonitis and liver dysfunction, in the combined tace and mwa group (56%) was comparable to the corresponding rate of the tace group (p > 0.411). the median and mean pfs of the tace group were significantly lower than those of the combined tace and mwa group (19.00 months vs. 29.00 months, 21.076 months vs. 24.693 months, p = 0.019, log-rank test).

技术成功率为100%。联合tace和mwa组的cr率(65%)高于单纯tace组(46%)。而联合组(56%)与单纯tace组的肝脓肿、自发性细菌性腹膜炎、肝功能障碍等常见不良事件发生率相当(p > 0.411)。单纯tace组的pfs中位数和平均值显著低于联合tace和mwa组(19.00个月和 29.00个月,21.076个月和 24.693个月,p = 0.019, log-rank检验)。


stereotactic dynact-guided mwa is a safe and effective method for the treatment of shcc, which usually provides an effective tumor puncture path, notably for lesions that cannot be detected following tace. overall, the data suggested that this treatment method could improve the clinical outcome of patients with shcc.

立体定向动态ct引导wma技术是一种安全有效的治疗shcc的方法,能提供一种有效的肿瘤穿刺路径,尤其是对于tace术后无法检测到的病变。综上所述,本研究数据表明该治疗方法可以提高shcc患者的临床疗效。


本文译者殷亮

中国科学技术大学附属第一医院(安徽省省立医院) 介入放射科

原文链接:https://mp.weixin.qq.com/s/bpngnwyi9hn6bwalvynpgq