the objective behind this study was to determine that assessment for retreatment with transarterial chemoembolization (art) score is really applicable in patients with hepatocellular carcinoma.
a cross sectional observational study was conducted on all patients with hepatocellular carcinoma of intermediate stage and undergone ≥2 transarterial chemoembolization. art score was assessed before and after each session of transarterial chemoembolization. multi-logistic regression analysis was performed to compare the final outcome of patients with art score of ≥2.5 into groups with two and more than two trans-arterial chemo-embolization sessions.
a total of 100 hcc patients were recruited for final analysis. our study participants consisted of total 100 hcc patients. mean child pugh score was 6.1±0.95. in our study, most of the study participants (n=63) had art score of less than 1.5 as compared to art score >2.5 (n=37). a significant proportion of patients with art score of <1.5 prior to second trans-arterial chemo-embolization had better median survival as compared to patients with art score of >2.5, p-value<0.001. patients with art score of more than 2.5 did not show any survival benefit after having 3rd or 4th trans-arterial chemo-embolization session, p=0.47.
our study findings suggest that those hcc patients who receive multiple sessions of tace with a low art score have more favourable outcomes with increased survival rate.