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520例肝癌患者行deb-ag捕鱼平台

文字: 2018-7-12    浏览次数:820    

background:this study aimed to investigate the difference of common adverse events (aes) between patients experienced first drug-eluting beads transarterial chemoembolization (deb-tace; fd) and second or higher deb-tace(shd), and the factors influencing aes.

背景:本研究旨在探讨患者首次行药物洗脱微球经动脉化疗栓塞术(deb-tacefd)与第二次或二次以上行deb-tace术(shd)常见不良事件(aes)的差异及影响aes的因素。


methods: five hundred twenty deb-tace records were retrospectively reviewed in this cohort study,among which 284 and 236 records were in fd and shd groups, respectively. the incidence and/or severity of pain, fever, vomiting, and increased blood pressure(bp) were collected.

方法:对520例行deb-tace术患者记录进行回顾性分析,其中fd和shd组分别为284和236个记录。收集疼痛、发热、呕吐和血压升高的发生率和/或严重程度。


results: pain numerical rating scale (nrs) score, pain severity, body temperature, fever severity, and fever lasting days were higher in fd group than in shd group, while no difference of vomiting and increased bp between 2 groups were disclosed. age ≥65 years was associated with decreased high fever and less possibility of vomiting in fd group, and lower pain and fever severity in shd group;male decreased the possibility of vomiting in both the groups, and reduced increased bp incidence in shd group;diabetes history correlated with decreased pain degree and less fever in fd group.

结果:fd组疼痛数值评定量表评分、疼痛严重度、体温、发热严重度、发热持续天数均高于shd组,而呕吐和血压升高两组间无差异。患者年龄≥65岁,在fd组,与高烧降低、呕吐减少相关,在shd组,与疼痛及发热的严重度降低相关。两组男性呕吐的可能性均降低,在shd组,男性血压升高的发生率降低。糖尿病病史与fd组疼痛程度降低及发热减少有关。  


conclusions: 
in conclusion, shd was better tolerated compared with fd in liver cancer patients, and older ageas well as male were correlated with less occurrence or severity of common aes in deb-tace operation.

结论:与fd相比,肝癌患者对shd的耐受性更好,大龄患者与男性两个因素同deb-tace手术中常见aes的低发生率或严重程度相关。